Supernatural, Doctor Who, Sherlock, Supernatural, Phantom of the Opera, Emma Approved, but honestly Supernatural.
The first words out of your mouth are two brothers.
Two brothers drive across America in a kickass car and fight monsters.
Two brothers go on a search for their father and hunt evil things.
Two brothers stop the apocalypse and save the world.
Two brothers, saving people, hunting things.
Two brothers — and the rest is all extra.